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GenoExplorer™ microRNA System

GenoExplorer™ microRNA Probe Set

GenoExplorer™ microRNA probe set provides specific and functionally validated miRNA probes for microarrays. Probes were designed based on the full miRNA sequences, computed with their lengths, Tm, and secondary structure. The probes are amine-modified oligonucleotides and they are ideally suited for most types of slide chemical substrates (eg. epoxy, aldehyde and NHS ester). The probe set contains both mature and precursor miRNA sequences as well as multiple positive and negative controls. Probe set features

  • GenoExplorer™ microRNA probe set provides specific and functionally validated miRNA probes for microarrays
  • Probes were designed based on the full miRNA sequences, computed with their lengths, Tm, and secondary structure
  • The probes are amine-modified oligonucleotides and they are ideally suited for most types of slide chemical substrates (eg. epoxy, aldehyde and NHS ester)
  • The probe set contains updated miRNA sequences with mature and most precursor probes (miRBase v14) as well as multiple positive and negative controls, for human over 1300 miRNA probes, mouse and rat over 1200 probes, and more species. Probe set features
  • Cat # Product Name Description Size Price
    1401C GenoExplorer™ microRNA probe set - human 1 complete GenoExplorer™ microRNA probe set for human in 384-well plates 500 pmol US$2,000
    1411C GenoExplorer™ microRNA probe set - mouse/rat 1 complete GenoExplorer™ microRNA probe set for mouse in 384-well plates 500 pmol US$2,000
    1421C GenoExplorer™ microRNA probe set - C. elegans 1 complete GenoExplorer™ microRNA probe set for C. elegans in a 384-well plate 500 pmol US$2,000
    1431C GenoExplorer™ microRNA probe set - Drosophila melanogaster 1 complete GenoExplorer™ microRNA probe set for Drosophila melanogaster in a 384-well plate 500 pmol US$2,000
    1441C GenoExplorer™ microRNA probe set - Arabidopsis thaliana 1 complete GenoExplorer™ microRNA probe set for Arabidopsis thaliana in a 384-well plate 500 pmol US$2,000
    1499 GenoExplorer™ microRNA for other species 1 complete GenoExplorer™ microRNA probe set in 384-well plates   Call for pricing

    Technical Resources

    Assay performance and technical bulletins provide experiment data on product performance

    General information about the product kits describes product design and assay performance

    Probe list on arrays (for Catalog 1100C's, 1200C's and 1400C's representing Sanger miRBase v15) human, mouse and rat, C.elegans, Drosophila, and Arabidopsis

    Probe list on arrays (for Catalog 1100v8's, 1200v8's and 1400v8's representing Sanger miRBase v8.2 and 9.1) human, mouse, rat, C.elegans, Drosophila, Arabidopsis

    Gal file is available for array image gridding (for catalog 1100v8’s and 1200v8’s)

    human, mouse/rat, C.elegans, Drosophila, and Arabidopsis

    General information about full service describes product design and assay performance
    Full service data output format demonstrates data output and format

    Full service data output format demonstrates data output and format

    Selected recent publications (GenoSensor reference):

    • Li G et al. Modulation of inflammatory markers by miR-146a during replicative senescence in trabecular meshwork cells. Invest Ophthalmol Vis Sci 2010; Jan 6

    • Hanoun N et al. The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic cancinogenesis. Clin Chem 2010; Apr 29

    • Liang Z et al. Involvement of miR-326 in chemotherapy resistance of breast cancer. Biochem Pharmacol 2010; 79(6):817-24

    • Liu X et al. microRNA-138 suppresses invasion and promotes apoptosis in head and neck squamous cell carcin. Cancer Lett2009; 286(2):217-22

    • Lee S-O et al. MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis in a rat model of polycystic kidney diseases. J Clin Invest 2008; 18(11):3714-24

    • Chang SS et al. miRNA alterations inhead and neck squamous cell carcinoma. Int J Cancer 2008; 123,2791-7

    • Park CS and Tang SJ. Regulation of microRNA Expression by Induction of Bidirectional Synaptic Plasticity. J Mol Neurosci. 2008; Nov 8

    • Chen X-M et al. A cellular miRNA, let-7i, regulates toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection. J. Biol. Chem. 2007; July 27

    • Baroukh N etc. MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta -cells lines. J Biol Chem 2007; Apr 26

    • Weston MD et al. MicroRNA gene expression in the mouse inner ear.
    Brain Res 2006; 1111(1)95-104

    Contact us if you want to order or have more questions.

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